We are interested in using mechanical force to trigger chemical transformations in polymers. Our recent research has focused on exploring how polymer architecture influences chain scission and mechanophore (a force-responsive moiety) activation. Specifically, we are interested in tuning mechanochemical reactivity by changing various architectural parameters. We are also interested in exploring solid-state polymer mechanochemistry with ball-mill grinding. Despite its long history in this field, important strides can still be made in improving our understanding of influential parameters, how polymers degrade, and differences with other mechanochemistry techniques.